Le Saux O, McNeish I, D'Incalci M, Narducci F, Ray-Coquard I.
Int J Gynecol Cancer. 2025 Feb 5;35(3):101667.
doi: 10.1016/j.ijgc.2025.101667. Online ahead of print.
PMID: 39987717 Review.
Abstract
High-grade serous carcinoma is the most lethal gynecological malignancy. Although serous tubal intra-epithelial carcinoma is increasingly recognized as a precursor to high-grade serous carcinoma, its optimal management remains controversial. This review examines the controversies in serous tubal intra-epithelial carcinoma pathogenesis, diagnosis, management, and follow-up, highlighting the need for collaboration, standardized guidelines, and further research to improve patient outcomes.
Keywords: Carcinogenesis; Ovarian Cancer; Preneoplastic Lesion.
